Feverfew Medicinal Use – Side Effects and More

Feverfew medicinal uses have gained attention among people seeking natural remedies for various health conditions. This perennial plant, scientifically known as feverfew tanacetum parthenium, belongs to the daisy family and has been valued in traditional medicine for centuries. Native to southeastern Europe, feverfew now grows throughout North America and Europe.

The herb’s popularity stems from its potential to address migraine attacks and reduce inflammation naturally. While scientific research continues to explore the full scope of feverfew’s benefits, many individuals have incorporated this herb into their health care routines.

What is Feverfew and How Does It Work?

Feverfew tanacetum parthenium is a flowering perennial plant that produces small, daisy-like white flowers with yellow centers. The plant grows up to two feet tall and releases a strong, bitter aroma when its leaves are crushed. 

Studies suggest that feverfew inhibits the production of inflammatory substances in the body. These anti inflammatory effects occur when the herb blocks certain proteins that trigger inflammation and pain responses. The plant may also affect blood vessel dilation and platelet activity, which could explain its potential benefits for migraine sufferers.

The beneficial effect of feverfew appears to stem from multiple mechanisms working together. Research indicates the herb may reduce prostaglandin synthesis and histamine release. Additionally, feverfew may influence serotonin levels, which play a role in migraine development.

Medicinal Uses of Feverfew

The primary feverfew medicinal uses focus on migraine attacks. Many people report that regular use has reduced the frequency of their migraines significantly. A landmark study found that feverfew users experienced significant protection against migraine attacks. The herb may also decrease the intensity of pain, nausea, and light sensitivity associated with these headaches.

Beyond migraines, feverfew shows promise for managing rheumatoid arthritis symptoms. The plant’s anti inflammatory effects may help reduce joint pain and swelling. Some individuals use fresh leaves or extract of feverfew to address general inflammatory conditions.

Laboratory studies indicate that parthenolide may inhibit certain malignant cell growth. These findings are limited to laboratory settings and do not suggest any benefit for humans.

Additional traditional uses include:

• Fever reduction (though modern research doesn’t strongly support this)
• Menstrual cramp relief
• Digestive support
• General pain management

Feverfew’s Efficacy: What Do Studies Suggest?

Scientific research on the efficacy of feverfew presents mixed but generally positive results. Several clinical trials have examined how feverfew affects migraine frequency and severity. A 2015 Cochrane review of multiple studies found that participants taking feverfew experienced fewer migraine attacks compared to those taking placebos.

One notable clinical trial showed that feverfew reduced migraine frequency by approximately 24% in regular users. A German study using CO2 extract found significant reduction in migraine attacks with specific dosing. The beneficial effect appeared most pronounced in individuals who experienced frequent migraines. Participants also reported less severe symptoms when migraines did occur.

However, not all studies suggest consistent benefits. Some trials found minimal differences between feverfew and placebo groups. These varying results may stem from differences in:

• Feverfew preparation methods
• Dosage amounts
• Parthenolide content
• Study duration
• Participant characteristics

Research into feverfew’s effects on rheumatoid arthritis remains limited. While laboratory studies show promising anti inflammatory effects, a 1989 human trial found no significant improvements. Long term studies are particularly needed to establish feverfew’s role in arthritis management.

Potential Side Effects of Feverfew

While feverfew is generally well-tolerated, side effects can occur, particularly with extended use. Clinical studies report the most common issues affect the digestive system, including stomach upset, nausea, and diarrhea. Some people experience mouth ulcers when chewing fresh leaves directly.

Allergic reactions may develop in individuals sensitive to plants in the daisy family. Symptoms include skin rashes, itching, and breathing difficulties. People with allergies to ragweed, chrysanthemums, or marigolds should exercise caution.

Additional side effects to consider:

• Nervousness or anxiety
• Sleep disturbances
• Muscle stiffness
• Joint pain
• Headache rebound when stopping suddenly

Certain groups should avoid feverfew entirely. Pregnant women shouldn’t use the herb as it may cause uterine contractions. Breastfeeding mothers should also abstain due to insufficient safety data. Anyone taking blood-thinning medications needs medical consultation before using feverfew.

How to Use Feverfew: Dosage and Forms

Feverfew comes in several forms, each with specific preparation methods and dosages. Fresh leaves represent the traditional approach, though their bitter taste makes them unpalatable for many. Dried leaves, capsules, and liquid extracts offer more convenient alternatives.

For those seeking natural nervous system supplements, standardized feverfew products typically contain 0.2% to 0.4% parthenolide. Studies have used various dosage recommendations including:

• Dried leaves: 50-100 mg daily 
• Fresh leaves: 2-3 small leaves daily 
• Standardized extract: Follow manufacturer guidelines

The extract of feverfew often provides more consistent potency than whole leaf preparations. Tablets and capsules eliminate the taste issue while maintaining effectiveness. Some people prefer tinctures or teas, though these may have variable concentrations.

Starting with lower doses helps assess tolerance. Taking feverfew with food may reduce stomach upset. Consistency matters more than timing, so choosing a regular schedule improves results.

Feverfew for Migraines: What You Need to Know

Research suggests that feverfew may prevent migraine attacks rather than treat acute episodes. The herb works best when taken daily for several months. Many migraine sufferers notice reduced frequency within 4-6 weeks of regular use.

Clinical trials indicate feverfew may decrease migraine occurrence by 20-30% in responsive individuals. The herb appears particularly helpful for those experiencing frequent attacks. Benefits often include reduced pain intensity and shorter duration when migraines do occur.

Success rates vary among users, and feverfew doesn’t work for everyone. Maintaining consistent daily intake proves crucial for effectiveness.

Feverfew and Arthritis: Potential Benefits

The anti inflammatory effects of feverfew theoretically support its use for rheumatoid arthritis management. Laboratory studies demonstrate that feverfew compounds may reduce inflammatory markers associated with joint damage. These findings suggest potential for symptom relief.

However, human trials haven’t consistently shown significant improvements in arthritis symptoms. More research is needed to determine optimal dosing and identify which arthritis patients might benefit most.

Long-Term Use of Feverfew: What to Consider

Extended feverfew use requires careful consideration and monitoring. While many people safely use the herb for months or years, long term effects aren’t fully understood. Regular users should watch for developing sensitivities or reduced effectiveness over time.

Withdrawal symptoms may occur when stopping feverfew suddenly after prolonged use. These can include rebound headaches, anxiety, and muscle tension. Gradually reducing the dose over several weeks helps minimize these effects.

For those interested in comprehensive support, products like N-Balance 8 offer balanced nervous system support alongside targeted remedies.

Conclusion

Feverfew medicinal uses show promise, particularly for migraine prevention and potentially for managing inflammatory conditions. While studies suggest beneficial effects, individual responses vary significantly. The herb’s anti inflammatory properties and relatively mild side effect profile make it an option worth considering for appropriate candidates.

Anyone interested in trying feverfew should consult healthcare providers first, especially those with existing conditions or taking medications. Natural remedies work best as part of comprehensive health care approaches.